About the variability, quality and reproducibility of ChIP-seq data
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولImpact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data
With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-seq throughput, the development of working standards for the quality assessment of ChIP-seq studies has received significant attention. The ENCODE consortium's large scale analysis of transcription factor binding and epigenetic marks as well as concordant work on ChIP-seq by other laboratories has establis...
متن کاملLarge-Scale Quality Analysis of Published ChIP-seq Data
ChIP-seq has become the primary method for identifying in vivo protein-DNA interactions on a genome-wide scale, with nearly 800 publications involving the technique appearing in PubMed as of December 2012. Individually and in aggregate, these data are an important and information-rich resource. However, uncertainties about data quality confound their use by the wider research community. Recentl...
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ژورنال
عنوان ژورنال: ScienceOpen Research
سال: 2016
ISSN: 2199-1006
DOI: 10.14293/s2199-1006.1.sor-life.argghm.v1